Little Known Facts About ceesdekker.
Little Known Facts About ceesdekker.
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Using one-molecule optical and AFM imaging and pressure-spectroscopy strategies, we look for to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our investigation interests include:
Human Rad51 filaments on double- and solitary-stranded DNA: correlating frequent and irregular types with recombination purpose.
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
Sculpting nano-electrodes with a transmission electron beam for electrical and geometrical characterization of nanoparticles.
That may be a dream of mine and we set to operate having a mouth watering dose of naivety. This really is something which will most likely yield breathtaking brings about the lengthier expression, but that doesn't matter. You should not only want to operate on the queries of tomorrow, and also on the queries with the working day after tomorrow.’
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is that these parts together make up a dwelling method. The trick of explained life, I feel, lies in the interactions, the interplay of Those people molecules. The large problem in regards to the origin of life continues to be unanswered. How did we at any time evolve from easy molecules in the extremely intricate systems we see right now? We do cees dekker not know. I want to work on These types of big, open issues.’
Nanopores characterize a sublime and multipurpose Software to evaluate one molecules. We exploration novel detection modes with stable-point out nanopores together with several solutions to evaluate proteins with nanopores. Assignments encompass the next:
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Quite neat, but that wasn’t actually wherever my interest lay. I wished to pioneer And that i experienced the sensation that was not probable, because the most intriguing elementary insights experienced already been uncovered. But my area experienced formulated many fascinating new instruments to evaluate person molecules. I decided which i needed to apply this to biology, to look at it from a Bodily viewpoint.’
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2013, managed shaping of Dwell bacterial cells into arbitrary styles; and discovery of spontaneous fluctuations while in the handedness of histone tetrasomes