The Single Best Strategy To Use For ceesdekker
The Single Best Strategy To Use For ceesdekker
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Rotary motion of DNA rotors on nanopores. Top row: raw video with the Cy5 channel of each rotor. Center row: corresponding single-particle localization success of equally ends on the DNA rotors. The place of the present frame is marked as orange and blue dots, plus the trajectory of the 10 frames before The present body is proven as good traces.
It was only inside the nineties although, when nanotechnology experienced Superior into a stage the place solitary molecules may very well be manipulated, that the main experimental equipment commenced to look.
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
Non-equilibrium folding of particular person DNA molecules recaptured around a thousand moments within a good condition nanopore
2010, developed a brand new way (‘wedging transfer’) to control nanostructures; 1st report of DNA translocation as a result of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
We form microorganisms into kinds that deviate from their organic phenotype. Especially, I will show our power to form Dwell E. coli microorganisms into novel shapes such as rectangles, squares, triangles and circles.
Nanopores depict a chic and functional Resource to measure one molecules. We investigate novel detection modes with solid-state nanopores as well as various ways to measure proteins with nanopores. Jobs encompass the subsequent:
‘You should not just think of the issues of tomorrow, and also look at the issues of your working day immediately after tomorrow’
Dekker begun his exploration on solitary carbon nanotubes in 1993 when he set up a completely new line of investigation to study electrical transportation by means of single organic and natural molecules among nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was realized within a collaboration with the team of Nobel laureate Richard Smalley. STM and nanolithography methods were being accustomed to reveal that these nanotubes are quantum wires at The only-molecule amount, with fantastic physical Houses.
Given that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from research of DNA loop extrusion and supercoiling to DNA translocation as a result of nanopores. Far more lately his investigate has focused on researching chromatin construction and mobile division with germs on chip, though he can be attempting to eventually Construct artificial cells from the bottom up.
Many new phenomena ended up identified, and he and his research team set up a number one position On this industry of analysis. Dekker and his exploration group identified new physics of nanotubes and explored the feasibility of molecular electronics. In 1998, they had been the 1st to build a transistor depending on one nanotube molecule.
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Dekker heeft ceesdekker fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style and design in 2005. (nl)